Voltage-Gated Ion Channels as Drug Targets

Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry)

Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry)
By David J. Triggle, Murali Gopalakrishnan, David Rampe, Wei Zheng, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

Publisher: Wiley-VCH
Number Of Pages: 492
Publication Date: 2006-04-17
ISBN-10 / ASIN: 3527312587
ISBN-13 / EAN: 9783527312580
Binding: Hardcover

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.

After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.

For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.

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